Description: The progesterone receptor (PgR) is an estrogen-regulated protein. It has been proposed that determination of PgR expression with help of zhis antibody indicates a responsive ER pathway, and therefore, may predict likely response to endocrine therapy in human breast cancer. A number of studies have shown that PgR determination provides supplementary information to ER, both in predicting response to endocrine therapy and estimating survival. PgR has proved superior to ER as a prognostic indicator in some studies.